Prospective validation of right ventricular role in primary graft dysfunction after lung transplantation
نویسندگان
چکیده
منابع مشابه
Influence of right ventricular function on the development of primary graft dysfunction after lung transplantation.
BACKGROUND Primary graft dysfunction (PGD) remains a significant cause of lung transplant postoperative morbidity and mortality. The underlying mechanisms of PGD development are not completely understood. This study analyzed the effect of right ventricular function (RVF) on PGD development. METHODS A retrospective analysis of a prospectively assessed cohort was performed at a single instituti...
متن کاملPrimary Graft Dysfunction After Lung Transplantation.
Primary graft dysfunction is a form of acute injury after lung transplantation that is associated with significant short- and long-term morbidity and mortality. Multiple mechanisms contribute to the pathogenesis of primary graft dysfunction, including ischemia reperfusion injury, epithelial cell death, endothelial cell dysfunction, innate immune activation, oxidative stress, and release of infl...
متن کاملLong Term Impact of Primary Graft Dysfunction after Lung Transplantation
According to the International Society for Heart and Lung Transplantation (ISHLT) Registry, graft failure accounted for 24.7% of deaths within 30 days of transplantation among adult lung recipients between 1992 and 2012 [1]. Although important details distinguishing different causes of early graft failure may be missing from the Registry data, it is likely that primary graft dysfunction (PGD) i...
متن کاملUPDATE IN INTENSIVE CARE: TRANSPLANTS Primary graft dysfunction after lung transplantation
Lung transplantation is a therapeutic option for pulmonary diseases in which the other treatment options have failed or in cases of rapid disease progression. However, trans-plantation is not free from complications, and primary graft dysfunction is one of them. Primary graft dysfunction is a form of acute lung injury. It characteristically develops during the immediate postoperative period, be...
متن کاملPlasma intercellular adhesion molecule-1 and von Willebrand factor in primary graft dysfunction after lung transplantation.
Primary graft dysfunction (PGD), a form of acute lung injury occurring within 72 h following lung transplantation, is characterized by pulmonary edema and diffuse alveolar damage. We hypothesized that higher concentrations of intercellular adhesion molecule-1 (ICAM-1) and von Willebrand factor (vWF) would be associated with the occurrence of PGD. A total of 128 lung transplant recipients among ...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2016
ISSN: 0903-1936,1399-3003
DOI: 10.1183/13993003.02136-2015